منابع مشابه
Comparing Tolerability and Efficacy of Generic versus Brand Alendronate: A Randomized Clinical Study in Postmenopausal Women with a Recent Fracture
INTRODUCTION An increasing number of generic alendronate formulations have become available. Although expected to have the same tolerability and efficacy, head-to head comparison of generic and brand alendronate was never performed. Therefore, we compared the tolerability and efficacy of generic and brand alendronate. METHODS In a randomized double-blinded single centre cross-over study in 37...
متن کاملNickel alendronate
The title compound {sys-tematic name: bis(μ(2)-dihydrogen 4-aza-niumyl-1-hy-droxy-butane-1,1-di-phos-pho-n-ato)bis-[aqua-(dihydrogen 4-aza-nium-yl-1-hy-droxy-butane-1,1-diphospho-n-ato)nickel(II)] dihydrate}, [Ni(2)(C(4)H(12)NO(7)P(2))(4)(H(2)O)(2)]·2H(2)O, was synthesiized under hydro-thermal conditions. Its structure is isotypic with the Co(II) analogue. The crystal structure is built up from...
متن کاملAlendronate Attenuates Eosinophilic Airway
Bisphosphonates (BPs) have been widely used to treat osteoporosis. They act by inhibiting farnesyl diphosphate synthase in the mevalonate pathway. This resembles the action of statins, whose immune-modulating effect has recently been highlighted. In contrast , the effect of BPs on immune responses has not been elucidated well. In this study, we examined the effect of alendronate (ALN), a nitrog...
متن کاملAlendronate sodium and uveitis
Alendronate sodium (Fosamax®) is a bisphosphonate that acts as a specific inhibitor of osteoclast mediated bone resorption. Bisphosphonates are synthetic analogues of pyrophosphate that bind to hydroxyapatite. The Dutch Medicine Evaluation Board approved alendronate sodium10 mg in April 1996. This formulation is indicated for the treatment and prevention of osteoporosis in women after menopause...
متن کاملHypoparathyroidism unmasked by alendronate.
The case of an elderly woman is reported in whom alendronate, given for osteoporosis, led to severe hypocalcaemia a few days after starting the drug treatment. This was caused by the unmasking of previously unrecognised hypoparathyroidism.
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ژورنال
عنوان ژورنال: BMJ
سال: 1998
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.316.7141.1389a